Contrast-associated Acute Kidney Injury

作者: Steven D. Weisbord , Paul M. Palevsky

DOI: 10.1016/J.CCC.2015.06.008

关键词: Iodinated contrastMedicineSequelaIntensive care medicineKidney diseaseIncidence (epidemiology)Renal functionAcute kidney injuryDiabetes mellitusNephrologyInternal medicine

摘要: Acute kidney injury (AKI) is a well-recognized iatrogenic sequela of intravascular iodinated contrast media administration. The incidence contrast-associated acute (CA-AKI) varies depending on the threshold change in function used to define renal and clinical characteristics risk profile patient population. CA-AKI typically manifests as relatively small, transient decrements that occur within 2–4 days A growing number studies suggest this condition associated with serious adverse outcomes, including death accelerated longer term loss function; however, causal nature these associations remains unknown. This important recent data demonstrate indicated contrast-enhanced procedures are not performed some patients chronic disease, likely out concern by providers for development CA-AKI. one few potentially preventable forms injury; result, there has been substantial interest identifying strategies reduce condition. Past research multiple pharmacological non-pharmacological interventions current evidence basis prevention Given an aging population, prevalence disease diabetes, increasing reliance diagnostic therapeutic utilize contrast, AKI remain common complication contrast. As it essential caring undergoing recognize factors for, outcomes with,

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