Role of quorum sensing and chemical communication in fungal biotechnology and pathogenesis.

作者: Jorge Barriuso , Deborah A Hogan , Tajalli Keshavarz , María Jesús Martínez

DOI: 10.1093/FEMSRE/FUY022

关键词: Quorum sensingBacteriaBiologyDimorphic fungusPopulationYeastMulticellular organismBiotechnologyBiofilmFungus

摘要: Microbial cells do not live in isolation their environment, but rather they communicate with each other using chemical signals. This sophisticated mode of cell-to-cell signalling, known as quorum sensing, was first discovered bacteria, and coordinates the behaviour microbial population a cell-density-dependent manner. More recently, these mechanisms have been described eukaryotes, particularly fungi, where regulate processes such pathogenesis, morphological differentiation, secondary metabolite production biofilm formation. In this manuscript, we review information available to date on yeast, dimorphic fungi filamentous fungi. We analyse diverse 'languages' used by different groups possible cross-talk interkingdom interactions organisms. discuss existence multicellular organisms, ecophysiological role QS fungal colonisation potential applications biotechnology pathogenesis.

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