Lung Nodules in Melanoma Patients: Morphologic Criteria to Differentiate Non-Metastatic and Metastatic Lesions.

摘要: Lung nodules are frequent findings in chest computed tomography (CT) patients with metastatic melanoma. In this study, we assessed the frequency and compared morphologic differences of metastases benign nodules. We retrospectively evaluated 85 melanoma (AJCC stage III or IV). Inclusion criteria were ≤20 lung follow-up using CT ≥183 days after baseline. for size morphology. Nodules significant growth, nodule regression line RECIST assessment histologic confirmation judged to be metastases. A total 438 evaluated, which 68% At least one metastasis was found 78% patients. 10 mm diameter cut-off (used RECIST) showed a specificity 95% sensitivity 20% diagnosing Central location (n = 122) more common (p 0.009). Subsolid morphology 53) < 0.001), calcifications 13) solely non-metastatic 0.001). Our data show that prevalent about two-thirds III/IV) majority Even though few indicators nodules, has limited value predict presence