Brain abscess associated with Aggregatibacter actinomycetemcomitans: case report and review of literature

摘要: Introduction: Aggregatibacter actinomycetemcomitans is considered a major pathogen in localized and generalized aggressive periodontitis. A. has been found various extra oral infections most frequently endocarditis. We report patient with multiple brain abscesses due to infection review the English language literature related this subject. Case report: A 42-year-old no underlying medical conditions presented lesions initially thought be metastatic of tumour unknown origin. Findings during drainage subsequent histopathological conclusions made more likely. Culture drained material remained negative; however, 16S rDNA polymerase chain reaction sequence analysis on direct revealed as causative agent infection. The likely source was poor dentition patient. After repeated antibiotic treatment gradually improved, although cognitive impairment remained. Conclusions: Our illustrates that dental condition, notably destructive periodontal disease, can risk for life-threatening thus contributes total inflammatory burden body.