Structure of the NF-κB transcription factor: a holistic interaction with DNA
作者： John Kuriyan , Dimitris Thanos
DOI: 10.1016/S0969-2126(01)00143-5
关键词: Promoter 、 Response element 、 Transcription factor II B 、 DNA-binding domain 、 Sp3 transcription factor 、 General transcription factor 、 RNA polymerase II 、 Molecular biology 、 Biology 、 Cell biology 、 Eukaryotic transcription
摘要: An unexpected mode of binding to DNA is revealed in two crystal structures a transcription factor that essential for many signalling pathways eukaryotic cells.
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sci-hub.se 参考文章(46)
E.B. Traenckner, S. Wilk, P.A. Baeuerle, A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B. The EMBO Journal. ,vol. 13, pp. 5433- 5441 ,(1994) , 10.1002/J.1460-2075.1994.TB06878.X
M. Naumann, C. Scheidereit, Activation of NF-kappa B in vivo is regulated by multiple phosphorylations. The EMBO Journal. ,vol. 13, pp. 4597- 4607 ,(1994) , 10.1002/J.1460-2075.1994.TB06781.X
N.D. Perkins, N.L. Edwards, C.S. Duckett, A.B. Agranoff, R.M. Schmid, G.J. Nabel, A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. The EMBO Journal. ,vol. 12, pp. 3551- 3558 ,(1993) , 10.1002/J.1460-2075.1993.TB06029.X
B. Stein, A.S. Baldwin, D.W. Ballard, W.C. Greene, P. Angel, P. Herrlich, Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. The EMBO Journal. ,vol. 12, pp. 3879- 3891 ,(1993) , 10.1002/J.1460-2075.1993.TB06066.X
Gourisankar Ghosh, Gregory Van Duyne, Sankar Ghosh, Paul B. Sigler, Structure of NF-kappa B p50 homodimer bound to a kappa B site. Nature. ,vol. 373, pp. 303- 310 ,(1998) , 10.1038/373303A0
W Kaszubska, R Hooft van Huijsduijnen, P Ghersa, A M DeRaemy-Schenk, B P Chen, T Hai, J F DeLamarter, J Whelan, Cyclic AMP-independent ATF family members interact with NF-kappa B and function in the activation of the E-selectin promoter in response to cytokines. Molecular and Cellular Biology. ,vol. 13, pp. 7180- 7190 ,(1993) , 10.1128/MCB.13.11.7180
C Kunsch, C A Rosen, NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Molecular and Cellular Biology. ,vol. 13, pp. 6137- 6146 ,(1993) , 10.1128/MCB.13.10.6137
R P Ryseck, P Bull, M Takamiya, V Bours, U Siebenlist, P Dobrzanski, R Bravo, RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B. Molecular and Cellular Biology. ,vol. 12, pp. 674- 684 ,(1992) , 10.1128/MCB.12.2.674
B Stein, P C Cogswell, A S Baldwin, Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction. Molecular and Cellular Biology. ,vol. 13, pp. 3964- 3974 ,(1993) , 10.1128/MCB.13.7.3964
Vincent Bours, Juanita Villalobos, Parris R. Burd, Kathleen Kelly, Ulrich Siebenlist, Cloning of a mitogen-inducible gene encoding a kappa B DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs. Nature. ,vol. 348, pp. 76- 80 ,(1990) , 10.1038/348076A0