Nanofiber Scaffolds as Drug Delivery Systems to Bridge Spinal Cord Injury.

作者: Angela Faccendini , Barbara Vigani , Silvia Rossi , Giuseppina Sandri , Maria Cristina Bonferoni

DOI: 10.3390/PH10030063

关键词: NeuroregenerationDrug deliverySpinal cord injuryRegeneration (biology)Therapeutic approachNeuroscienceSpinal cordAnesthesiaMedicineNeuroprotectionNanofiber

摘要: … A primary mechanical injury in the spinal cord triggers a cascade of secondary events, … involve the use of nanofibers as local drug delivery systems. Drugs released by nanofibers aim at …

参考文章(176)
Jing Qu, Dan Wang, Huihui Wang, Yunhai Dong, Feng Zhang, Baoqi Zuo, Huanxiang Zhang, Electrospun silk fibroin nanofibers in different diameters support neurite outgrowth and promote astrocyte migration. Journal of Biomedical Materials Research Part A. ,vol. 101, pp. 2667- 2678 ,(2013) , 10.1002/JBM.A.34551
Ji-hye Lee, Young Jun Lee, Hyeong-jin Cho, Heungsoo Shin, Guidance of in vitro migration of human mesenchymal stem cells and in vivo guided bone regeneration using aligned electrospun fibers. Tissue Engineering Part A. ,vol. 20, pp. 2031- 2042 ,(2014) , 10.1089/TEN.TEA.2013.0282
Liliana R. Pires, Vincenzo Guarino, Maria J. Oliveira, Cristina C. Ribeiro, Mário A Barbosa, Luigi Ambrosio, Ana Paula Pêgo, Ibuprofen-loaded poly(trimethylene carbonate-co-ε-caprolactone) electrospun fibres for nerve regeneration Journal of Tissue Engineering and Regenerative Medicine. ,vol. 10, ,(2016) , 10.1002/TERM.1792
Šárka Kubinová, Daniel Horák, Aleš Hejčl, Zdeněk Plichta, Jiří Kotek, Vladimír Proks, Serhiy Forostyak, Eva Syková, SIKVAV‐modified highly superporous PHEMA scaffolds with oriented pores for spinal cord injury repair Journal of Tissue Engineering and Regenerative Medicine. ,vol. 9, pp. 1298- 1309 ,(2015) , 10.1002/TERM.1694
Ravinder Pannu, Douglas K. Christie, Ernest Barbosa, Inderjit Singh, Avtar K. Singh, Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury. Journal of Neurochemistry. ,vol. 101, pp. 182- 200 ,(2006) , 10.1111/J.1471-4159.2006.04354.X
Shushi Kabu, Yue Gao, Brian K. Kwon, Vinod Labhasetwar, Drug Delivery, Cell-Based Therapies, and Tissue Engineering Approaches for Spinal Cord Injury Journal of Controlled Release. ,vol. 219, pp. 141- 154 ,(2015) , 10.1016/J.JCONREL.2015.08.060
Sara Gnavi, Benedetta Fornasari, Chiara Tonda-Turo, Rossella Laurano, Marco Zanetti, Gianluca Ciardelli, Stefano Geuna, The Effect of Electrospun Gelatin Fibers Alignment on Schwann Cell and Axon Behavior and Organization in the Perspective of Artificial Nerve Design International Journal of Molecular Sciences. ,vol. 16, pp. 12925- 12942 ,(2015) , 10.3390/IJMS160612925
Robert Lanza, Robert Langer, Joseph P Vacanti, Anthony Atala, Principles of tissue engineering Elsevier Academic Press. ,(2014)
Nicholas A. Peppas, A practical approach to bodybuilding Nature. ,vol. 389, pp. 453- 453 ,(1997) , 10.1038/38940
M Yan, Y-w Liu, W Shao, X-g Mao, M Yang, Z-x Ye, W Liang, Z-j Luo, EGb761 improves histological and functional recovery in rats with acute spinal cord contusion injury Spinal Cord. ,vol. 54, pp. 259- 265 ,(2016) , 10.1038/SC.2015.156