Best supportive care or chemotherapy for stage IV non-small cell lung cancer

摘要: Although cisplatin-based chemotherapy regimens were introduced in the late 1970s for management of advanced non-small cell lung cancer, more than 15 years randomized trials required to produce convincing data showing survival improvement comparison best supportive care alone. The routine use this indication is still object considerable debate Europe and North America as reflected by different recent editorials or reviews (Haskel 1991; Souhami 1996; Vokes 1995; White Souquet et al. Sorensen 1997).