Engineered mesenchymal stem cells as vectors in a suicide gene therapy against preclinical murine models for solid tumors.
作者： Ikrame Amara , Elodie Pramil , Catherine Senamaud-Beaufort , Audrey Devillers , Rodney Macedo
DOI: 10.1016/J.JCONREL.2016.08.019
关键词: Suicide gene 、 Bystander effect 、 Cancer research 、 Cytotoxic T cell 、 Ex vivo 、 Immune system 、 CYP2B6 、 Mesenchymal stem cell 、 In vivo 、 Pharmacology 、 Biology
摘要: … Mice which exhibited weak luminescence on day 1 at the beginning of the study were the ones with the weakest luminescence at days 3 and 6 as well. The very weak luminescence in …
sci-hub.se 参考文章(44)
Qi Bao, Yue Zhao, Hanno Niess, Claudius Conrad, Bettina Schwarz, Karl-Walter Jauch, Ralf Huss, Peter J. Nelson, Christiane J. Bruns, Mesenchymal Stem Cell-Based Tumor-Targeted Gene Therapy in Gastrointestinal Cancer Stem Cells and Development. ,vol. 21, pp. 2355- 2363 ,(2012) , 10.1089/SCD.2012.0060
Ikrame Amara, Walid Touati, Philippe Beaune, Isabelle de Waziers, Mesenchymal stem cells as cellular vehicles for prodrug gene therapy against tumors. Biochimie. ,vol. 105, pp. 4- 11 ,(2014) , 10.1016/J.BIOCHI.2014.06.016
Tian-Yuan Zhang, Bing Huang, Zhong-Yue Yuan, Yu-Lan Hu, Yasuhiko Tabata, Jian-Qing Gao, None, Gene recombinant bone marrow mesenchymal stem cells as a tumor-targeted suicide gene delivery vehicle in pulmonary metastasis therapy using non-viral transfection Nanomedicine: Nanotechnology, Biology and Medicine. ,vol. 10, pp. 257- 267 ,(2014) , 10.1016/J.NANO.2013.06.003
Philipp Renner, Elke Eggenhofer, Przemyslaw Slowik, Edward K. Geissler, Pompiliu Piso, Hans J. Schlitt, Marc H. Dahlke, Felix C. Popp, Mesenchymal stem cells as immunomodulators after liver transplantation Liver Transplantation. ,vol. 15, pp. 1192- 1198 ,(2009) , 10.1002/LT.21862
Nayoun Kim, Seok-Goo Cho, Clinical applications of mesenchymal stem cells. The Korean Journal of Internal Medicine. ,vol. 28, pp. 387- 402 ,(2013) , 10.3904/KJIM.2013.28.4.387
Marina Tychopoulos, Laurent Corcos, Philippe Genne, Philippe Beaune, Isabelle de Waziers, A virus-directed enzyme prodrug therapy (VDEPT) strategy for lung cancer using a CYP2B6/NADPH-cytochrome P450 reductase fusion protein. Cancer Gene Therapy. ,vol. 12, pp. 497- 508 ,(2005) , 10.1038/SJ.CGT.7700817
Faranak Salman Nouri, Xing Wang, Arash Hatefi, Genetically engineered theranostic mesenchymal stem cells for the evaluation of the anticancer efficacy of enzyme/prodrug systems Journal of Controlled Release. ,vol. 200, pp. 179- 187 ,(2015) , 10.1016/J.JCONREL.2015.01.003
Ezio Gerdoni, Barbara Gallo, Simona Casazza, Silvia Musio, Ivan Bonanni, Enrico Pedemonte, Renato Mantegazza, Francesco Frassoni, Gianluigi Mancardi, Rosetta Pedotti, Antonio Uccelli, Mesenchymal stem cells effectively modulate pathogenic immune response in experimental autoimmune encephalomyelitis Annals of Neurology. ,vol. 61, pp. 219- 227 ,(2007) , 10.1002/ANA.21076
Khalid Shah, Mesenchymal stem cells engineered for cancer therapy. Advanced Drug Delivery Reviews. ,vol. 64, pp. 739- 748 ,(2012) , 10.1016/J.ADDR.2011.06.010
Christine M. Barbon, Min Yang, Gregory D. Wands, Radha Ramesh, Barbara S. Slusher, Mary Lynne Hedley, Thomas M. Luby, Consecutive low doses of cyclophosphamide preferentially target Tregs and potentiate T cell responses induced by DNA PLG microparticle immunization Cellular Immunology. ,vol. 262, pp. 150- 161 ,(2010) , 10.1016/J.CELLIMM.2010.02.007