THE TREATMENT OF MAMMARY DYSPLASIA WITH SPECIAL REFERENCE TO MICROCYSTIC AND MACROCYSTIC DISEASE OF THE BREAST.

摘要: Abstract There are three forms of mammary dysplasia: 1. Mastodynia (simple nodosity with pain) is the most common and least serious. One case carcinoma, only, was found in 350 patients this disease. 2. Macrocystic disease next form dysplasia. In 445 patients, followed for five years or more, only cases (1 per cent) carcinoma ultimately occurred group. 3. Microcystic (adenosis) breast is, fortunately, dysplasia, since it serious many its aspects. 150 microcystic (adenosis), adequately followed, incidence cancer 3 cent. a control population, chance that white women between age thirty-five forty-four will develop, lies 2.8 5.5 1,000 [69]. Breast changes due to dysplasia intimately related function ovaries, result from an imbalance activities follicle hormone complex corpus luteum hormone. promoting factors, namely estrogen, bringing about directly concerned progression certain cancers. The following observations were pointed out indicate possible relationship associated development cancer: (1) cases, breasts removed because show some chronic cystic mastitis (breast dysplasia); (2) suggestive transitional stages have been traced by investigators; (3) while experimental production adenosis not possible, date, higher order mammalia, has accomplished rats mice using estrogenic hormones; (4) among treated conservatively cent developed subsequently. This seven times expected rate. Forms treatment discussed. If on exploration breast, radical mastectomy choice. Simple rarely choice should be used removing unless extenuating circumstances health palliation supervene.