Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells.

作者: R. Albrechtsen , M. H. Nielsen , N. E. Skakkebaek , U. Wewer

DOI: 10.1111/J.1699-0463.1982.TB00097_90A.X

关键词: OrganelleVesicleGerm cell tumorsUltrastructureCytoplasmBiologyCell biologyCarcinoma in situGerm line developmentGerm cell

摘要: The two cytoplasmic organelles, dense-cored vesicles and "nuages" have been considered to allow positive identification of primordial germ cells in rodents, but no use these potential markers has applied human material. We observed the abnormal carcinoma situ testis thus brought further evidence for cell origin this lesion. These organelles may be useful study tumors.

参考文章(8)
L. C. Stevens, Experimental production of testicular teratomas in mice. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 52, pp. 654- 661 ,(1964) , 10.1073/PNAS.52.3.654
E. M. Eddy, Judy M. Clark, Daniel Gong, Bruce A. Fenderson, Origin and migration of primordial germ cells in mammals Gamete Research. ,vol. 4, pp. 333- 362 ,(1981) , 10.1002/MRD.1120040407
T. Fukuda, Chr. Hedinger, P. Groscurth, Ultrastructure of developing germ cells in the fetal human testis. Cell and Tissue Research. ,vol. 161, pp. 55- 70 ,(1975) , 10.1007/BF00222114
Niels E. Skakkebæk, Jørgen G. Berthelsen, Carcinoma-in-situ of the testis and invasive growth of different types of germ cell tumours. A revised germ cell theory. International Journal of Andrology. ,vol. 4, pp. 26- 33 ,(1981) , 10.1111/J.1365-2605.1981.TB00647.X
NielsE. Skakkebæk, POSSIBLE CARCINOMA-IN-SITU OF THE TESTIS The Lancet. ,vol. 300, pp. 516- 517 ,(1972) , 10.1016/S0140-6736(72)91909-5
F. K. MOSTOFI, Pathology of Germ Cell Tumors of Testis: A Progress Report. Cancer. ,vol. 45, pp. 1735- 1754 ,(1980) , 10.1002/CNCR.1980.45.S7.1735