Relief of Idiopathic Generalized Pruritus in Dialysis Patients Treated with Activated Oral Charcoal

摘要: The effect of oral charcoal on idiopathic generalized pruritus in 11 stable patients undergoing maintenance hemodialysis was compared to that placebo dextrose a controlled, double-blind, cross-over study. Contrasted placebo, charcoal, 6 g daily for 8 weeks, relieved subjectively all but one patient (P = 0.01). Symptomatic relief from coincided with objective resolutions active, scratch-induced skin lesions 0.03). No significant alterations were noted the serum concentrations standard laboratory variables, including lipids, alkaline phosphatase, phosphorus, or calcium, during treatment either placebo. adverse effects