Patent blue sentinel node mapping in cervical cancer patients may lead to decreased pulse oximeter readings and positive methaemoglobin results.

摘要: Summary Bac/zground and objective: Patent blue (4-[(4-diethylaminophenyl)-(4-diethyla2aniumylidencyclohexa-2,5-clienyliden) methyl]-6-hydroxy-3-sulfo-benzolsulfonate, sodium salt) is a contrast dye used for the intraoperative detection of primary lymphatic nodes draining area tumour infiltration. The known to interact with pulse oximeter readings. However, degree alteration seems be moderate predictable when patent injected into perimammilar region during breast surgery. Met/oods: Here we report severe interference anaesthetic monitoring was cervix prior laparoscopy-assisted radical vaginal hysterectomy cervical cancer. Resu/ts: Injection induced rapid (within 14 ± 9 min after injection) (from 5=98% 89 2%) decrease in readings, accompanied by positive methaemoglobin values 7.3 2.5% (arterial co-oximetry, Bayer Rapidlab 865 blood gas analyser; Bayer, Fernwald, Germany). Control these different device (Radiometer ABL co-oximeter Radiometer, Willich, Germany) yielded negative results (<1.7%, mean 0.9 — 0.6%). arterial PO2 normal all patients throughout procedure. Conc/usion: uteri interferes dramatically This situation further complicated device-depend ent co-oximetry results. For time being it recommendable monitor adequate oxygenation patient presence regular control PO2. Clearly, unresolved issue reliable determination remains matter clinical concern anaesthetists.