Oxidative Stress and Cancer

作者: Amitava Dasgupta , Kimberly Klein

DOI: 10.1016/B978-0-12-405872-9.00008-2

关键词: CancerLipid peroxidationEndocrinologyBiologyLipid peroxideOxidative stressInternal medicineCatalase8-HydroxyguanosineOvarian cancerSkin cancer

摘要: Oxidative stress is linked to various types of cancer. It has been postulated that oxidative damage DNA primarily responsible for promoting Overproduction oxygen free radicals demonstrated in breast, bladder, colon, liver, pancreatic, prostate, and skin Moreover, elevated blood tissue concentration 8-hydroxydeoxyguanosine (8-OHdG), a marker damage, associated with poor outcome patients ovarian Patients renal cell carcinoma also have increased stress, as revealed by concentrations lipid peroxide blood, whereas the antioxidant enzyme catalase reduced. This chapter discusses evidence linking leukemia.

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