Gap junction function
作者： Paolo Meda , David C. Spray
DOI: 10.1016/S1569-2558(00)30008-X
关键词: Chemistry 、 Biophysics 、 Gap junction 、 Function (biology) 、 Nanotechnology 、 Coupling (electronics)
摘要: Publisher Summary This chapter discusses the functions of gap junction. The considers methodological requirements for investigating junction functions, problems that complicate such studies, and new tools experimental strategies may aid in this quest. presents an overview to highlight notion what a does is exchange ions molecules among cells. these channels subserve different tissues are determined by diffusion most relevant those tissues, methods measurement or not assess critical molecules. also reviews some evidence pointing specific variety normal pathological organs tissues. paramount function junction-mediated intercellular communication provide pathway diffusional small hydrophilic from one cell next. strength coupling determines efficiency any molecule which junctional permeant be used probe function.
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