Cytokines in exertion-induced skeletal muscle injury

作者: Joseph G. Cannon , Barbara A. St. Pierre

DOI: 10.1023/A:1006828425418

关键词: Skeletal muscleNecrosisIntracellularExertionCytokine secretionRegeneration (biology)MyocyteBiologyTumor necrosis factor alphaImmunology

摘要: Cytokines are a diverse family of intercellular signaling proteins that influence the movement, proliferation, differentiation, metabolism and membrane processes target cells. Synthesis release cytokines from leukocytes in response to microbial stimuli well known. This review, however, will present evidence non-infectious can induce cytokine secretion other cells (including muscle cells) following myocellular injury. The biological actions potential adaptive values these through course necrosis regeneration be described.

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