Detection of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma

作者: Yangyang Wang , Francesco Sabbatino , Xinhui Wang , Soldano Ferrone

DOI: 10.1007/978-1-62703-727-3_28

关键词: AntibodyCancer researchTumor antigenCSPG4AntigenMelanomaImmunotherapyChondroitin Sulfate Proteoglycan 4ImmunohistochemistryChemistry

摘要: The tumor antigen chondroitin sulfate proteoglycan 4 (CSPG4) appears to be a useful biomarker identify melanoma cells and an attractive target apply antibody-based immunotherapy for the treatment of melanoma. Here we described reverse transcription-polymerase chain reaction (RT-PCR) method immunohistochemical (IHC) staining detect expression CSPG4 in tissues.

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