Lupus nephritis improvement after anti-tumor necrosis factor alpha monoclonal antibody (infliximab) treatment for Crohn's disease: a case report.

摘要: Association between Crohn's disease (CD) and lupus nephritis is very rare and, to the best of our knowledge, it has been described only once. We report here a clinical case CD occurred in young woman 8 years after diagnosis according clinical, laboratory histological criteria. was unresponsive steroids immunosuppressants therefore, patient treated with anti-tumour necrosis factor alpha monoclonal antibody (Infliximab). This therapy led remission both (50% Disease Activity Index--CDAI--decrease) (disappearance pyuria absence infection, significant increase serum albumin improvement renal function tests). The immunological background diseases be taken into account explain either association two disorders or therapeutic response. Moreover, this confirms extends concept that patients more accurate detection autoimmune associated required.