Genome-Wide Expression Profiling Deciphers Host Responses Altered during Dengue Shock Syndrome and Reveals the Role of Innate Immunity in Severe Dengue

作者: Stéphanie Devignot , Cédric Sapet , Veasna Duong , Aurélie Bergon , Pascal Rihet

DOI: 10.1371/JOURNAL.PONE.0011671

关键词: Innate immune systemImmunologyGene expression profilingDNA microarrayDengue shock syndromeVirologyDengue feverInflammationSystemic inflammatory response syndromeImmune systemBiology

摘要: Background Deciphering host responses contributing to dengue shock syndrome (DSS), the life-threatening form of acute viral infections, is required improve both differential prognosis and treatments provided DSS patients, a challenge for clinicians.

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