Sequential Waves of Gene Expression in Patients with Clinically Defined Dengue Illnesses Reveal Subtle Disease Phases and Predict Disease Severity
作者： Zhining Wang , Brett M. Forshey , Amy C. Morrison , Gloria Sierra , Isabel Bazan
DOI: 10.1371/JOURNAL.PNTD.0002298
关键词:
摘要: Background Dengue virus (DENV) infection can range in severity from mild dengue fever (DF) to severe hemorrhagic (DHF) or shock syndrome (DSS). Changes host gene expression, temporally through the progression of DENV infection, especially during early days, remains poorly characterized. Early diagnostic markers for DHF are also lacking.
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