作者: T.M. Sørensen , C.R. Bjørnvad , G. Cordoba , P. Damborg , L. Guardabassi
DOI: 10.1111/JVIM.15048
关键词: Urinary system 、 Microbiological culture 、 Predictive value of tests 、 Medical prescription 、 Dipstick 、 Urinalysis 、 Internal medicine 、 Antibiotics 、 Medicine 、 Prospective cohort study
摘要: BACKGROUND: Clinical signs of urinary tract disease in dogs often lead to prescription antibiotics. Appropriate diagnostic work‐up could optimize treatment and reduce the risk inappropriate use HYPOTHESIS/OBJECTIVES: To describe evaluate impact on decision treat (DTT) choice antibiotic (COT) for presenting with clinical disease. ANIMALS: One hundred fifty‐one 52 Danish veterinary practices. METHODS: Prospective, observational study. signs, work‐up, prescriptions were recorded. Urine samples submitted a reference laboratory quantitative bacterial culture (QBC) susceptibility testing. The results used as assessing appropriateness DTT COT. RESULTS: In majority dogs, veterinarians performed dipstick (99%), microscopic examination urine (80%) (56%). Fifty‐one percent had infection (UTI) based QBC. was made 62% while 36% over‐prescribed 2% under‐prescribed. Inappropriate second‐line agents found 57% UTI cases. Performing microscopy—but not culture—significantly impacted (P = 0.039) no difference seen COT (P = 0.67). accuracy in‐house microscopy 64.5 77%, respectively. Conclusions Importance: Over‐prescription antibiotics common among suspected UTI, regardless performed. Test inaccuracy under practice conditions incoherence between test decision‐making both explained unnecessary