Four new sesquiterpenes from Commiphora myrrha and their neuroprotective effects.
作者： Jing Xu , Yuanqiang Guo , Peng Zhao , Ping Guo , Yonggang Ma
DOI: 10.1016/J.FITOTE.2012.03.016
关键词: Two-dimensional nuclear magnetic resonance spectroscopy 、 Burseraceae 、 Sesquiterpene 、 Stereochemistry 、 Chemistry 、 Commiphora myrrha 、 Neuroprotection
摘要: Four new sesquiterpenes, myrrhterpenoids K-N (1-4) have been isolated from the resin of Commiphora myrrha. Their structures and relative configurations were elucidated by spectroscopic methods (IR, ESIMS, HR-ESIMS, 1D 2D NMR). Compounds 1 4 showed neuroprotective effects against MPP(+)-induced neuronal cell death in SH-SY5Y cells.
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