Vaccination studies of aspergillosis in turkeys: subcutaneous inoculation with several vaccine preparations followed by aerosol challenge exposure.

摘要: Five vaccines were prepared from an isolate of Aspergillus fumigatus: a culture filtrate vaccine (I), spore (II), mycelial (III), and 2 germling (IV V). The produced on different media. Two experiments conducted to test the for efficacy in groups 21 turkey poults by giving each bird subcutaneous inoculations respective at 1 weeks age. birds challenge exposed aerosol spores A fumigatus month differed only exposure. In experiment 1, 38% protected when vaccinated with (IV) dose aerosolized that killed 100% nonvaccinated controls. Onset postchallenge-exposure deaths delayed days turkeys given IV. 2, 48% IV, whereas 62% 86% 3 other died. 50% (III) protected. Torticollis was frequent sign disease 2.