Epidermal growth factor-toxin A chain conjugates: EGF-ricin A is a potent toxin while EGF-diphtheria fragment A is nontoxic.
作者： Daniel B. Cawley , Harvey R. Herschman , D. Gary Gilliland , R. John Collier
DOI: 10.1016/0092-8674(80)90366-9
关键词: Orders of magnitude (mass) 、 Epidermal growth factor 、 Biology 、 Toxin 、 Biochemistry 、 Diphtheria toxin 、 Conjugate 、 Clostridium difficile toxin A 、 Biological activity 、 Ricin
摘要: … Diphtheria toxin is secreted as a single polypeptide chain by … The toxin is readily nicked by proteolysis to form two … RTA conjugate is a potent toxin, killing cells at concentrations …
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