Depression and adipose essential polyunsaturated fatty acids
作者： G. Mamalakis , M. Tornaritis , A. Kafatos
关键词: Fatty acid 、 Internal medicine 、 Depression scale 、 Polyunsaturated fatty acid 、 Multiple linear regression analysis 、 Adipose tissue 、 Fish oil 、 Biology 、 Depression (differential diagnoses) 、 Docosahexaenoic acid 、 Endocrinology
摘要: Abstract The objective of the present study was to investigate relation between adipose tissue polyunsaturated fatty acids, an index long-term or habitual acid dietary intake, and depression. sample consisted 247 healthy adults (146 males, 101 females) from island Crete. number subjects with complete data on all variables studied 139. Subjects were examined at Preventive Medicine Nutrition Clinic University Depression assessed through use Zung Self-rating Scale. Mildly depressed had significantly reduced (−34.6%) docosahexaenoic (DHA) levels than non-depressed subjects. Multiple linear regression analysis indicated that depression related negatively DHA levels. In line findings other studies, observed negative depression, in study, appears indicate increasing intakes decreasing This is first literature report a has been reported be associated increased cytokine production, such as IL-1, IL-2, IL-6, INF-γ INF-α. On hand, fish oil omega-3 acids have inhibit synthesis. therefore, may stem inhibiting effect
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