作者: A. Ahmed Ezzat , H. Saito , T. Sawada , T. Yaegashi , Y. Goto
DOI: 10.1016/J.ANIREPROSCI.2010.06.002
关键词: Follicle-stimulating hormone 、 Gonadotropic cell 、 Luteinizing hormone 、 Hormone 、 Testosterone 、 Prolactin 、 Chemistry 、 Anterior pituitary 、 Endocrinology 、 Kisspeptin 、 Internal medicine
摘要: Abstract The aims of the present study were to clarify effect Kisspeptin-10 (Kp10) on secretion luteinizing hormone (LH), follicle-stimulating (FSH) and prolactin (PRL) from bovine anterior pituitary (AP) cells evaluate ability sex steroids enhance sensitivity gonadotropic lactotropic Kp10. AP prepared 7-week-old male calves incubated for 12 h with estradiol (E2; 10−8 M), progesterone (P4; testosterone (T; or vehicle only (control), then 2 h Kp10 (10−6 M). amounts LH, FSH PRL released into culture medium after 2-h incubation period examined. significantly stimulated LH treated E2 T (P results suggest that T, but not P4, in response However, had no stimulatory regardless steroids. directly stimulates cells, do Furthermore, LH- FSH-releasing PRL-releasing are less potent than GnRH TRH, respectively.