Dynamics of Cdk1 Substrate Specificity during the Cell Cycle
作者： Mardo Kõivomägi , Ervin Valk , Rainis Venta , Anna Iofik , Martin Lepiku
DOI: 10.1016/J.MOLCEL.2011.05.016
关键词: Biochemistry 、 CDC2 Protein Kinase 、 Cyclin 、 Cell cycle 、 Active site 、 Consensus site 、 Binding site 、 Biology 、 Cyclin-dependent kinase 、 Cyclin-dependent kinase 1 、 Cell biology
摘要: … several Cln2-, Clb3-, and Clb2-specific Cdk1 targets. We propose that robust timing and ordering of cell cycle events depend on gradual changes in the substrate specificity of Cdk1. …
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