Alternative splicing and expression of human and mouse NFAT genes.

作者: Hanna Vihma , Priit Pruunsild , Tõnis Timmusk

DOI: 10.1016/J.YGENO.2008.06.011

关键词: Alternative splicingGeneTranscription factorNFATNFATC2NFATC3In situ hybridizationMolecular biologyNFATC Transcription FactorsBiology

摘要: … and alternative splicing of the human and mouse NFAT genes, including novel splice … mouse and human tissues and brain regions by RT-PCR. Our results show that alternatively …

参考文章(54)
Naoko Arai, Esteban S. Masuda, Ryu Imamura, Toshiya Takano, Shin-ichiro Imai, Ken-ichi Arai, Yoshiyuki Naito, Tadahiro Fujino, CARBOXYL-TERMINAL 15-AMINO ACID SEQUENCE OF NFATX1 IS POSSIBLY CREATED BY TISSUE-SPECIFIC SPLICING AND IS ESSENTIAL FOR TRANSACTIVATION ACTIVITY IN T CELLS Journal of Immunology. ,vol. 161, pp. 3455- 3463 ,(1998)
Ann M. Ranger, Michael J. Grusby, Martin R. Hodge, Ellen M. Gravallese, Fabienne Charles de la Brousse, Tim Hoey, Craig Mickanin, H. Scott Baldwin, Laurie H. Glimcher, The transcription factor NF-ATc is essential for cardiac valve formation Nature. ,vol. 392, pp. 186- 190 ,(1998) , 10.1038/32426
A M Ho, J Jain, A Rao, P G Hogan, Expression of the transcription factor NFATp in a neuronal cell line and in the murine nervous system. Journal of Biological Chemistry. ,vol. 269, pp. 28181- 28186 ,(1994) , 10.1016/S0021-9258(18)46911-6
V. S. Seybold, L. G. Coicou, R. D. Groth, P. G. Mermelstein, Substance P initiates NFAT‐dependent gene expression in spinal neurons Journal of Neurochemistry. ,vol. 97, pp. 397- 407 ,(2006) , 10.1111/J.1471-4159.2006.03744.X
Simon Plyte, Marianna Boncristiano, Elena Fattori, Federico Galvagni, Silvia Rossi Paccani, M. Bernardetta Majolini, Salvatore Oliviero, Gennaro Ciliberto, John L. Telford, Cosima T. Baldari, Identification and Characterization of a Novel Nuclear Factor of Activated T-cells-1 Isoform Expressed in Mouse Brain Journal of Biological Chemistry. ,vol. 276, pp. 14350- 14358 ,(2001) , 10.1074/JBC.M007854200
Gerald R Crabtree, Eric N Olson, NFAT Signaling Cell. ,vol. 109, pp. S67- S79 ,(2002) , 10.1016/S0092-8674(02)00699-2
José Luis de la Pompa, Luika A. Timmerman, Hiroaki Takimoto, Hiroki Yoshida, Andrew J. Elia, Enrique Samper, Julia Potter, Andrew Wakeham, Luc Marengere, B. Lowell Langille, Gerald R. Crabtree, Tak W. Mak, Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum Nature. ,vol. 392, pp. 182- 186 ,(1998) , 10.1038/32419
E S Masuda, Y Naito, H Tokumitsu, D Campbell, F Saito, C Hannum, K Arai, N Arai, NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus. Molecular and Cellular Biology. ,vol. 15, pp. 2697- 2706 ,(1995) , 10.1128/MCB.15.5.2697
C Luo, E Burgeon, J A Carew, P G McCaffrey, T M Badalian, W S Lane, P G Hogan, A Rao, Recombinant NFAT1 (NFATp) Is Regulated by Calcineurin in T Cells and Mediates Transcription of Several Cytokine Genes Molecular and Cellular Biology. ,vol. 16, pp. 3955- 3966 ,(1996) , 10.1128/MCB.16.7.3955
José Aramburu, Joseph Heitman, Gerald R. Crabtree, Calcineurin: a central controller of signalling in eukaryotes EMBO Reports. ,vol. 5, pp. 343- 348 ,(2004) , 10.1038/SJ.EMBOR.7400133