Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice

作者: Elisa Giovannetti , Ayse Erozenci , Jorn Smit , Romano Danesi , Godefridus J. Peters

DOI: 10.1016/J.CRITREVONC.2011.03.010

关键词: CancerDrug resistancePharmacogeneticsDrug metabolismEpigeneticsMedicinemicroRNAPharmacologyCancer researchDrugCancer stem cell

摘要: Drug resistance remains a major problem in the treatment of cancer patients for both conventional chemotherapeutic and novel biological agents. Intrinsic or acquired resistance …

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