Anti-angiogenic and anti-tumoral properties of beta and gamma secretase inhibitors
作者： Daniel Paris , Michael J. Mullan
DOI:
关键词: Angiogenesis 、 Angiogenic Inhibition 、 Beta (finance) 、 Gamma secretase 、 Amyloid precursor protein 、 Medicine 、 Anti angiogenic 、 Amyloid precursor protein secretase 、 Pharmacology
摘要: The present invention relates to methods of treating tumors or proliferative disorders that are associated with angiogenesis by administering g-secretase and b-secretase inhibitors inhibit secretases involved in amyloid precursor protein processing. In particular, provided treat disorders, tumors, inflammatory animals humans need such treatment angiogenic inhibition, the animal human therapeutically effective amounts unit dosage form a composition containing carrier at least one inhibitor inhibits secretase APP
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