Anthocephalus cadamba (Roxb.) Miq., Rubiaceae, extract shows hypoglycemic effect and eases oxidative stress in alloxan-induced diabetic rats
作者： Mohammad A Alam , Nusrat Subhan , Sadia A Chowdhury , Mohammad A Awal , Mahbub Mostofa
DOI: 10.1590/S0102-695X2011005000033
关键词: Thiobarbituric acid 、 Oxidative stress 、 TBARS 、 Aspartate transaminase 、 Traditional medicine 、 Antioxidant 、 Catalase 、 Alloxan 、 Biochemistry 、 Alanine transaminase 、 Chemistry 、 General Pharmacology, Toxicology and Pharmaceutics
摘要: The hydroethanolic extract of the flowering tops Anthocephalus cadamba (Roxb.) Miq., Rubiaceae, a Bangladeshi medicinal plant, was studied for its potential hypoglycemic effect and antioxidant property in alloxan-induced diabetic rats. induced significant reduction serum glucose, transaminases, e.g. aspartate transaminase (AST), alanine (ALT) alkaline phosphatases (ALP), activities. Significant changes thiobarbituric acid reactive substances (TBARS), peroxidase catalase levels during experimental period were also observed. results established that A. possesses is able to protect liver brain from oxidative damages caused by diabetes.
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