c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities

作者: Stewart D. Lyman , Sten Eirik W. Jacobsen

DOI: 10.1182/BLOOD.V91.4.1101

关键词: Acute lymphocytic leukemiaCell growthGrowth factorHaematopoiesisCytokineCell biologyEndocrinologyInternal medicineEndothelial stem cellAdult stem cellProgenitor cellBiology

摘要: HEMATOPOIESIS IS A life-long process responsible for replenishing both hematopoietic progenitor cells and mature blood from a pool of pluripotent, long-term reconstituting stem cells.[1][1] The daily turnover in normal adult approximately 1012 is tightly regulated, involving,

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