A Survey of More Than 11 Years of Neurologic Diseases of Ruminants with Special Reference to Transmissible Spongiform Encephalopathies (TSEs) in Greece

作者: S. Leontides , V. Psychas , S. Aargyroudis , A. Giannati-stefanou , E. Paschaleri-papadopoulou

DOI: 10.1046/J.1439-0450.2000.00348.X

关键词: CoenurosisScrapiePhysical examinationPathologySpinal cordFlockBiologySerologyCattle DiseasesHelminths

摘要: The first cases of scrapie were detected in Greece a flock sheep October 1986. All the animals affected and all two flocks that contact killed buried. A systematic investigation available with signs indicating neurological disease started goats late 1986, as well cattle 1989. was based on clinical examination, necropsy or macroscopical examination brain viscera, histological except those coenurosis. Histological examinations specimens from spinal cord other tissues, if considered necessary bacteriological, toxicological serological also carried out. In 1997, diagnosed second (a mixed goats), grazing pasture close to place where initially detected. Diagnosis lesions, immunoblotting used. Distinctive lesions found and/or eight flocks. revealed stem cervical cord, tended be symmetrical. one sheep, severe cortex cerebral hemispheres cerebellum found. pathological isoform PrP protein Despite eradication scheme applied, reappeared after 11 years it occurred initially. This may indicate effectiveness implemented not adequate additional approaches needed.

参考文章(6)
IH Pattison, Fifty years with scrapie: a personal reminiscence. Veterinary Record. ,vol. 123, pp. 661- 666 ,(1988) , 10.1136/VR.123.26-27.661
T K Sklaviadis, L Manuelidis, E E Manuelidis, Physical properties of the Creutzfeldt-Jakob disease agent. Journal of Virology. ,vol. 63, pp. 1212- 1222 ,(1989) , 10.1128/JVI.63.3.1212-1222.1989
I. Zlotnik, The Histopathology of the Brain Stem of Sheep Affected with Natural Scrapie Journal of Comparative Pathology and Therapeutics. ,vol. 68, pp. 148- IN12 ,(1958) , 10.1016/S0368-1742(58)80016-8
Pavlos Toumazos, First report of ovine scrapie in Cyprus. British Veterinary Journal. ,vol. 144, pp. 98- 100 ,(1988) , 10.1016/0007-1935(88)90157-1
Pavlos Toumazos, Scrapie in Cyprus. British Veterinary Journal. ,vol. 147, pp. 147- 154 ,(1991) , 10.1016/0007-1935(91)90105-V