Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3
作者： Hua Zou , William J Henzel , Xuesong Liu , Alexis Lutschg , Xiaodong Wang
DOI: 10.1016/S0092-8674(00)80501-2
关键词: Caenorhabditis elegans 、 Biology 、 Apoptosome 、 Peptide sequence 、 Cytochrome 、 Caspase 3 、 Apoptosome assembly 、 Molecular biology 、 Cytochrome c 、 APAF1
摘要: We report here the purification and cDNA cloning of Apaf-1, a novel 130 kd protein from HeLa cell cytosol that participates in the cytochrome c–dependent activation of caspase-3. The …
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