Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145.
作者： Tony DeBlasio , Zhen Fan , Yang Lu , Ding Peng , John Mendelsohn
DOI:
关键词: Cell cycle 、 Growth factor receptor inhibitor 、 DU145 、 Epidermal growth factor receptor 、 Cancer research 、 Cancer cell 、 Epidermal growth factor 、 Transforming growth factor 、 Biology 、 Autocrine signalling
摘要: … DU145 has been demonstrated to be an Rbdeficient cell line (16). Therefore, we investigated the other Rb… This suggests that in these Rb-deficient cells, Rb-related protein p130 may be …
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