Intrahepatic cholestasis of pregnancy: an estrogen-related disease.

摘要: In the recent years new avenues have been opened in treatment of ICP, a complex disorder that seems to represent maladaptation some young and otherwise healthy women, estrogens or other sex hormones. New drugs shown capable providing promising therapeutic effects either on pruritus, main distressing symptoms cholestasis (such as epomediol, silymarin) both pruritus biochemical abnormalities UDCA). Future clinical experimental studies should provide better insight into pathogenesis cholestasis, mechanisms bile formation secretion, metabolism hormones their alteration relationship is highly prevalent humans.