Periarticular osteoporosis in osteoarthritis of the knee

作者: Félix Fernández-Madrid , Dorothy A. Nelson , Peter R. Miller , José L. Granda , Robert L. Karvonen

DOI:

关键词: ArthropathyDensitometryOsteoarthritisBone densityAnatomyBone diseaseBone mineralOsteoporosisKnee JointNuclear medicineMedicine

摘要: Objective. To test the hypothesis that bone mineral density (BMD) in periarticular subchondral regions of knee joint is abnormal patients with osteoarthritis (OA). Methods. Sixty-two knees from relatively mild OA (primarily radiographic grades 0, 1,2) were compared 62 normal subjects matched for age, sex, race, and body side (right or left). BMD lumbar spine, distal femoral shaft, several determined by dual energy x-ray absorptiometry (DXA). facilitate increased accuracy values, lateral DXA was also performed used to provide a third dimension usual two-dimensional anterior-posterior g/cm 2 , producing measurements as 3 . Subchondral included both superficial deep medial femoral, tibial, tibial compartments. Results. (g/cm ) lower than 6 (n = 43) white female (average decrease -13.3%), significant all ( p 0.001 0.047). Two-dimensional -7.3%), only (p 0.011 0.014). 19) African American -9.1%), one 0.016). There no difference spinal (Ll-L4) shaft between either racial group. About 13% had osteoporosis at spine. Conclusion. A present whether not they based on spine measurement.

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