Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load
作者： Florent Mouliere , Safia El Messaoudi , Celine Gongora , Anne-Sophie Guedj , Bruno Robert
DOI: 10.1593/TLO.12445
关键词: Mutation 、 Mutant 、 Allele 、 Circulating Cell-Free DNA 、 KRAS 、 Molecular biology 、 Real-time polymerase chain reaction 、 Pathology 、 Medicine 、 Colorectal cancer 、 Cell culture 、 Cancer research 、 Oncology
摘要: … We used a set of primers that amplifies targets of increasing size (82, 138, 200, 300, 355, and 390 bp) within the hot-spot region of the KRAS gene (codons 12 and 13 of exon 2) and in …
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