Prevalence of and risk factors for increased serum levels of allergen-specific IgE in a population of Norwegian dogs
作者： Annelin A Bjelland , Frederik L Dolva , Ane Nødtvedt , Bente K Sævik
DOI: 10.1186/S13028-014-0081-Z
关键词: Serology 、 Immunoglobulin E 、 Immunology 、 Atopic dermatitis 、 Population 、 Allergen 、 Medicine 、 Prevalence 、 Rottweiler 、 Breed
摘要: Background: The importance of different allergens in association with IgE production and canine atopic dermatitis (CAD) has been poorly studied few studies exist on factors influencing allergen-specific antibodies serum. aim this cross-sectional study was to investigate the prevalence elevated levels environmental Norwegian dogs a suspicion CAD. secondary identify risk associated serum IgE. Results: sample consisted from 1313 161 breeds. All samples were submitted for serologic IgE-testing (Fc epsilon R1 alpha-based ELISA) based Overall, 84.3% had one or more allergen(s). predominant amongst positive results indoor (Acarus siro 84.0%, Dermatophagoides farinae 80.2%, Tyrophagus putrescentiae 79.9%). Sheep sorrel most commonly encountered outdoor allergen (40.0%). Only 2.6% flea saliva. test varied significantly depending when taken. Samples taken during summer autumn often came out than winter spring. Geographical variations also demonstrated. A greater proportion females males results, tested allergens. mean age higher testing negative. breed. boxer only breed compared other Boxers allergens, whereas Rottweiler Conclusions: hypersensitivity Outdoor minor reactivity saliva rare. Breed differences identified. Season sampling, dogs’ geographical localisation, sex affected analysis.
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