Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
作者： Gijs Van Haaften , Gillian L Dalgliesh , Helen Davies , Lina Chen , Graham Bignell
DOI: 10.1038/NG.349
关键词: Cancer research 、 Histone H3 、 Methylation 、 Methyltransferase 、 Histone 、 Epigenetics 、 Mutation 、 Biology 、 Germline mutation 、 Demethylase
摘要: Somatically acquired epigenetic changes are present in many cancers. Epigenetic regulation is maintained via post-translational modifications of core histones. Here, we describe …
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