Growth Hormone and the Immune System
作者： Christoph J. Auernhammer , Martin Bidlingmaier , Christian J. Strasburger
DOI: 10.1007/978-1-4615-5163-8_13
关键词: Growth hormone deficiency 、 Receptor 、 Autocrine signalling 、 Growth hormone treatment 、 Insulin-like growth factor 、 Immune system 、 Cell biology 、 Growth hormone receptor 、 Paracrine signalling 、 Biology
摘要: Growth hormone (GH) and insulin like growth factor I (IGF-I) play an important role in the neuro-endocrine-immune crosstalk. GH IGF-I receptors are expressed on surface of immune cells. stimulate proliferation immunocompetent cells modulate several humoral cellular functions. In addition, also synthesized secreted by various Increasing evidence suggests, that “immune GH-IGF-I axis” acting a paracrine/autocrine system between has function, at least part may exert this function autonomously independent endocrine system.
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