Treatment of cancers having k-ras mutations
作者： Changgeng Qian , Rudi Bao , Chengjung Lai
DOI:
关键词: Kinase 、 HDAC inhibitor 、 Molecular biology 、 Biology 、 Mutation (genetic algorithm) 、 Cancer 、 RAS Mutation
摘要: The present invention provides a method of treating cancer associated with K- ras mutation in subject need thereof. comprises the steps (1) identifying K-ras mutation; and (2) adminsiterign to (i) an inhibitor PI3 kinase (ii) HDAC inhibitor, wherein are administered amounts which together therapeutically effective.
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