Taurine and epilepsy.

作者: Simo S. Oja , Pirjo Saransaari

DOI: 10.1016/J.EPLEPSYRES.2013.01.010

关键词: Inhibitory postsynaptic potentialAnimal speciesExcitatory postsynaptic potentialTaurineEpilepsyBiologyNeurosciencePharmacologyFree aminoTaurine deficiencyTaurine metabolism

摘要: Dysfunction of excitatory and inhibitory neurotransmitters or neuromodulators is thought to underlie epileptic symptoms. Taurine, 2-aminoethanesulfonate, a ubiquitous free amino acid abounding in the brain humans most animal species. It hyperpolarizes neurons inhibits their firing. may be participating factor certain subpopulations epilepsy patients but its deficiency not universal prerequisite for seizures. Here, participation taurine seizure models human reviewed.

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