p14ARF deletion and methylation in genetic pathways to glioblastomas.
作者： Mitsutoshi Nakamura , Takao Watanabe , Ulf Klangby , Charlotte Asker , Klas Wiman
DOI: 10.1111/J.1750-3639.2001.TB00388.X
关键词: Locus (genetics) 、 Methylation 、 Diffuse Astrocytoma 、 Cancer research 、 DNA methylation 、 Molecular biology 、 Immunohistochemistry 、 CDKN2A 、 p14arf 、 Biology 、 Gene
摘要: … In the present study, 59% of primary glioblastomas had either a p14ARF gene alteration or a … In contrast, 50% of secondary glioblastomas in which p53 mutations are a genetic hallmark (…
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