作者: Kilian Mellon , Chris Wright , Peter Kelly , C.H. Wilson Horne , David E. Neal
DOI: 10.1016/S0022-5347(01)67604-3
关键词: Clinical significance 、 Pathology 、 Internal medicine 、 Oncology 、 Epithelioma 、 Carcinoma 、 Urinary bladder 、 Immunohistochemistry 、 Epidermal growth factor receptor 、 Epidermal growth factor 、 Medicine 、 Bladder cancer
摘要: ABSTRACTFor bladder cancer we currently lack accurate methods of predicting outcome, although clinical stage and histological grade are broad determinants prognosis. Preliminary data have indicated that assessment epidermal growth factor receptor status is a method further subclassifying cancer. We assessed prospectively the significance determining in 212 patients with newly diagnosed who were followed for 1 to 96 months (mean 26.5). In multivariate analyses was confirmed be an independent predictor survival (p = 0.004) progression 0.0004). Most importantly, found 80% sensitive 93% specific T1, 3 conclude useful molecular marker cancer, especially those without infiltration de...