Managing Terrorism or Accidental Nuclear Errors, Preparing for Iodine-131 Emergencies: A Comprehensive Review

作者: Eric Braverman , Kenneth Blum , Bernard Loeffke , Robert Baker , Florian Kreuk

DOI: 10.3390/IJERPH110404158

关键词: Thyroid cancerMedicineInjury preventionThyroidPoison controlNuclear terrorismThyroid nodulesEnvironmental healthIodineGlobal health

摘要: Chernobyl demonstrated that iodine-131 (131I) released in a nuclear accident can cause malignant thyroid nodules to develop children within 300 mile radius of the incident. Timely potassium iodide (KI) administration prevent development cancer and American Thyroid Association (ATA) number United States governmental agencies recommend KI prophylaxis. Current pre-distribution by government other governments with reactors is probably ineffective. Thus we undertook thorough scientific review, regarding emergency response 131I exposures. We propose: (1) at risk populations; (2) prompt administration, 2 hours incident; (3) utilization lowest effective dose; (4) distribution extension least miles from epicenter potential (5) education public about dietary sources; (6) continued post-hoc analysis long-term impact accidents; (7) support for global iodine sufficiency programs. Approximately two billion people are deficiency disorder (IDD), world’s leading preventable brain damage. Iodide deficient individuals greater developing after exposure. There virtually no studies prophylaxis infants, adolescents, our target population. Because their sensitivity these side effects, have suggested should extrapolate adult dose, 15–30 mg or 1–2 per 10 pounds children. encourage health (private governmental) consider critical recommendations.

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