Adult hippocampal neurogenesis for systems consolidation of memory

摘要: The hippocampus (HPC) is required for the initial process of permanent memory formation. After acquisition, HPC-dependency recall gradually decreases with time, whereas cortical-dependency increases. This phenomenon often referred to as systems consolidation memory. In HPC, adult neurogenesis has been described in many mammalian species and involved learning this review, we first examine neural circuit mechanisms that underlie episodic memories, focusing on within HPC. Recently, several studies have examined characterization engram cells, their biochemical physiological changes, circuits Therefore, discuss possible role functional states speculate implications transition type psychiatric disorders such post-traumatic stress disorder.