Nucleotide sequence and control of transcription of the bacteriophage T4 motA regulatory gene.
作者： M. Uzan , E. Brody , R. Favre
DOI: 10.1111/J.1365-2958.1990.TB02059.X
关键词: Transcription (biology) 、 Gene 、 Biology 、 Gene product 、 Nucleic acid sequence 、 Promoter 、 Genetics 、 Open reading frame 、 Regulator gene 、 Conserved sequence
摘要: Summary A 2116bp segment of the bacteriophage T4 genome encompassing motA regulatory gene has been sequenced. In addition to motA, five open reading frames were identified in direction early transcription. The encodes a basic protein 211 amino acids with predicted molecular weight 23559. Measurements rate transcription showed that promoter this is turned off after only 2 min development. This presents structure which richer information than classical constitutive Escherichia coli promoter. containing conserved sequences centred at -10 and -35, shares extensive homologies other subgroups promoters regions +3 -55. We discuss possible role these different sequence determinants.
sci-hub.se 参考文章(48)
V de Franciscis, R Favre, M Uzan, J Leautey, E Brody, In vitro system for middle T4 RNA. II. Studies with T4-modified RNA polymerase. Journal of Biological Chemistry. ,vol. 257, pp. 4097- 4101 ,(1982) , 10.1016/S0021-9258(18)34690-8
Elisabeth Niggemann, Ian Green, Hans-Peter Meyer, Wolfgang Rüger, Physical mapping of bacteriophage T4 Molecular and General Genetics MGG. ,vol. 184, pp. 289- 299 ,(1981) , 10.1007/BF00272920
M. Uzan, J. Leautey, Y. d'Aubenton-Carafa, E. Brody, Identification and biosynthesis of the bacteriophage T4 mot regulatory protein. The EMBO Journal. ,vol. 2, pp. 1207- 1212 ,(1983) , 10.1002/J.1460-2075.1983.TB01568.X
Wai Mun Huang, The 52-protein subunit of T4 DNA topoisomerase is homologous to the gyrA-protein of gyrase. Nucleic Acids Research. ,vol. 14, pp. 7379- 7390 ,(1986)
W. Kammerer, U. Deuschle, R. Gentz, H. Bujard, Functional dissection of Escherichia coli promoters: information in the transcribed region is involved in late steps of the overall process. The EMBO Journal. ,vol. 5, pp. 2995- 3000 ,(1986) , 10.1002/J.1460-2075.1986.TB04597.X
A E Menkens, K N Kreuzer, Deletion analysis of bacteriophage T4 tertiary origins. A promoter sequence is required for a rifampicin-resistant replication origin. Journal of Biological Chemistry. ,vol. 263, pp. 11358- 11365 ,(1988) , 10.1016/S0021-9258(18)37965-1
Joyce Emrich Owen, Dennis W. Schultz, Andrew Taylor, Gerald R. Smith, Nucleotide sequence of the lysozyme gene of bacteriophage T4 Journal of Molecular Biology. ,vol. 165, pp. 229- 248 ,(1983) , 10.1016/S0022-2836(83)80255-1
John F. Pulitzer, Anna Coppo, Maurizia Caruso, Host-virus interactions in the control of T4 prereplicative transcription Journal of Molecular Biology. ,vol. 135, pp. 979- 997 ,(1979) , 10.1016/0022-2836(79)90523-0
E H Radany, L Naumovski, J D Love, K A Gutekunst, D H Hall, E C Friedberg, Physical mapping and complete nucleotide sequence of the denV gene of bacteriophage T4. Journal of Virology. ,vol. 52, pp. 846- 856 ,(1984) , 10.1128/JVI.52.3.846-856.1984
Hans-Dieter Liebig, Wolfgang Rüger, Bacteriophage T4 early promoter regions. Consensus sequences of promoters and ribosome-binding sites. Journal of Molecular Biology. ,vol. 208, pp. 517- 536 ,(1989) , 10.1016/0022-2836(89)90145-9