Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

作者: Myunggon Ko , Yun Huang , Anna M. Jankowska , Utz J. Pape , Mamta Tahiliani

DOI: 10.1038/NATURE09586

关键词:

摘要: … We transiently transfected HEK293T cells with Myc-tagged murine Tet2 and assessed 5mC and 5hmC levels by immunocytochemistry (Fig. 1 and Supplementary Figs 1–4). Myc–Tet2-…

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