The biology of HMG-CoA reductase: the pros of contra-regulation
作者： Randolph Hampton , Dago Dimster-Denk , Jasper Rine
DOI: 10.1016/S0968-0004(96)80168-X
关键词:
摘要: Hydroxymethylglutaryl-CoA reductase (HMG-R) is a key enzyme in the mevalonate pathway, from which thousands of molecules are derived including cholesterol and prenyl moieties. The regulation HMG-R complex includes feedback control, cross-regulation by independent biochemical processes contra-regulation separate isozymes. From studies yeast, these modes can be considered an integrated fashion.
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