Testicular biopsy. Contemporary interpretation

作者: Manuel Nistal , Ricardo Paniagua

DOI: 10.1016/S0094-0143(05)70200-7

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摘要: In contrast to the consensus regarding its utility in other organs, biopsy of testis is not universally accepted, and number testicular biopsies usually low. One possible reason subjectivity histologic diagnoses. For example, hypospermatogenesis (one most frequent diagnosis) may be diagnosed by pathologists as maturation arrest or even normal histology. As a result, many urologists have tried replace less aggressive techniques that supply indirect information state parenchyma, including hormonal assays, measurement size, studies correlating levels serum follicle-stimulating hormone (FSH), spermiogram. Such correlations are useful, particularly severe lesions, but there exceptions. Patients with large testes azoospermic, whereas patients small sperm counts. Similarly, correlation between FSH level count imperfect, slightly low high Indirect methods cannot always provide precise knowledge what occurring within testis. Successful use spermatids for vitro fertilization has generated renewed interest biopsy, it now used variety disorders. The pathologist reports on pathophysiology specimen. This methodology requires inclusion qualitative quantitative studies, evaluation lesion's evolution (prognosis), and, often, therapeutic advice treatment. Cooperation clinicians optimizes patient.

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